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Immunity to Botox - Fact or Fiction? Botox cosmetic injections generally work well for the vast majority of patients. Some patients report that they have developed resistance over time to teh drug with a lessened effect. Like all drugs, acquired immunity to Botox is both possible and enough clinical evidence exists that it is likely a real phenomenon. New And Different Procedures In Plastic Surgery The continued acceptance and demand for plastic surgery has created a demand for a number of different and unusual procedures. These newer plastic surgery procedures are more of a reflection of American society and culture than advancements in surgical technology. Plastic Surgery Treatments For Lip Wrinkles The development of upper lip lines and wrinkles is very troubling for most women as it is a sign of aging. Lip wrinkles are impossible to cureand any patient undergoing treatments should view the expected results more as improvement rather than elimination. Injectable fillers, Botox, and laser resurfacing are the mainstays of treatment today.